Genomics

Illustration of how the CRISPR COVID diagnostic works on a molecular level

Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes

Eliminating RNA amplification simplifies and speeds up assay for SARS-CoV-2 virus, making it ideal for point of care testing.

Professor Danielle Edwards with a tortoise on Galapagos

Continuing Darwin’s work on Galapagos Island

186 years after Darwin first described the Galapagos racer snake, Danielle Edwards seeks to rebuild their population by using DNA from one of his original samples.

Young Black woman in hospital room

FDA approves first test of CRISPR to correct genetic defect causing sickle cell disease

UC scientists and physicians hope to permanently cure patients of sickle cell disease by using CRISPR-Cas9 to replace a defective gene with the normal version.

Blue scale on a yellow background

Is this one protein responsible for weight gain?

Diminishing a single protein in a set of mice caused them to gain only half the weight of other mice, even on a high-fat diet.

Doudna reacts with surprise to her win

Jennifer Doudna wins 2020 Nobel Prize in chemistry

Jennifer Doudna, UC Berkeley and UCSF professor and Berkeley Lab faculty scientist, shares the prize with Emmanuelle Charpentier for their discovery of CRISPR-Cas9 as a tool for making targeted changes to the genome.

X chromosome floating in blue background

Scientists achieve first complete assembly of human X chromosome

The first end-to-end, completely gapless DNA sequence of a human chromosome is a major milestone for genomics.

Woman staring through transparent plastic at people wearing PPE

UC Berkeley launches trial of saliva test for COVID-19

Saliva can be gathered without medical supervision, unlike current tests, which saves time, money and precious PPE.

David Ardell

Researchers forge a new weapon to fight parasites and other infections

‘It’s a first step toward fulfilling the promise of the genomics era to inform how we combat disease,’ lead researcher says.

Cover of Nature

Most comprehensive study of whole cancer genomes completed

The Pan-Cancer Project discovers causes of unexplained cancers and zeros in on mechanisms of development.

Steaks on the grill

Why are humans the only species prone to heart attacks?

Gene loss 2 to 3 million years ago may explain why coronary events are common in humans but rare in other animals.

Pages